Regarding alcohol: Psalm 104:15 exclaims that God created wine to make the heart of man rejoice. Paul also told Timothy to take a "little wine" for his stomach and frequent cases of illness, and Jesus both turned water into wine and imbibed moderately himself from time to time (1 Tim 5:21). He was accused of being a glutton and winebibber, which wouldn't make much sense unless he ate food of some kind and drank wine to some degree. Of course the charges were false, but teetotalers normally don't get accused of being winebibbers unless there is some ulterior motive for making the charge or it could just be a mistaken view of the individual suffering the calumny.
John Chrysostom once observed:
"Drunkenness then surely does not arise from wine, but from intemperance. Wine is bestowed upon us for no other purpose than for bodily health; but this purpose also is thwarted by immoderate use."